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Side Effects of Wellbutrin

Did you know that there are side effects of Wellbutrin? Because they definitely are!

And you may be wondering if Wellbutrin can make you lose weight, as well as, other things this drug can help you with.

We’ve covered each of these below and many more that’ll interest you.

Therefore, if you’ve had any concerns before this time, you can look forward to having them answered in the best ways.

What is Wellbutrin?

Wellbutrin is an antidepressant also known as bupropion.

This drug is used in managing depression, affective disorder, and other conditions.

When taken orally, it gives instant release, sustained, or extended-release depending on the type of tablet that was taken.

Wellbutrin is quite unique from other antidepressants because it does not impact on the sexual function of the individual taking it.

That is why this drug may be prescribed to eliminate the nonsexual desires effect created by other drugs.

Nonetheless, this drug creates its own side effects and while it could be mild, there are cases where it may be intense.

Accordingly, it is important to know these side effects to ensure you can identify if it is the drug causing it when you take it.

What Are Side Effects of Wellbutrin?

The common side effects of Wellbutrin are not limited to agitation, insomnia, stomach pain, and dizziness.

Other side effects are dry mouth, vomiting, dizziness, sore throat, and muscle pain.

Asides from the aforelisted side effects, it is possible to experience the following:

  • Nausea
  • Vomiting
  • Diarrhea
  • Dizziness
  • Headache
  • Constipation
  • Stomach pain
  • Changes in appetite
  • Increased sweating
  • Increased urination

Severe Side Effects of Wellbutrin

There are also severe side effects that may stem from taking Wellbutrin.

Some of these symptoms are:

  • Fainting
  • Chest pain
  • Confusion
  • Dark urine
  • Hearing problems
  • Unusual swelling
  • Changes in vision
  • Yellow skin or eyes
  • Difficulty breathing
  • Trouble concentrating
  • Delusions or hallucinations
  • Rapid or irregular heartbeat
  • Fever, chills, or a sore throat
  • Changes in your menstrual cycle
  • Exaggerated feelings of well-being
  • Changes in sexual desire or function
  • Worsening depression and/or suicidal thoughts

Others are:

  • Hostility
  • Agitation
  • Seizures
  • Panic attacks
  • Impulsiveness
  • Aggressiveness
  • Severe headache
  • Inability to sit still
  • Pale-colored stools
  • Swollen, blistered, or peeling skin
  • Severe or lingering joint or muscle pain
  • Severe or lingering nausea, vomiting, or stomach pain
  • Severe or lingering nervousness, restlessness, or insomnia

Uses of Wellbutrin

Wellbutrin has various uses and for starters it is used in the treatment of the depressive disorder (MDD).

What’s more, this drug helps to treat the seasonal affective disorder (SAD).

There are also off label uses of this drug in the treatment of certain symptoms.

Some of these symptoms include bipolar disorder, attention-deficit/hyperactivity disorder (ADHD), obesity, social anxiety disorder, PTSD, and anxiety.

Wellbutrin is also an ingredient in Zyban, a brand of bupropion that helps people to quit smoking.

Doses of Wellbutrin

There are three doses of Wellbutrin and these are immediate-release, sustained-release, and extended-release.

Here’s an outline of each:

Immediate Release:

An immediate release is when the effect is felt after the drug has been taken.

As such, there is a regular formulation, known as Wellbutrin after being taken can have its effect felt shortly.

The formulation of the treatment of the major depressive disorder (MDD).

And the dosage to be taken is around 100mg twice a day and upon the doctor’s prescribed by a doctor, the number of times it should be taken can be increased.

Sustained Release:

There is a sustained version of Wellbutrin and this is known as Wellbutrin SR.

This version helps in the treatment of MDD.

The use of this formulation could be 150mg taken once a day, but it has been increased to 150mg  twice daily.

It can even be taken twice daily.


There is also Wellbutrin XL and it offers extended-release.

This formulation is used in the treatment of MDD  as well as SAD.

The prescribed dosage is around 300mg to 450mg and either of these can be consumed twice daily.


When substances are taken at the same time, interactions may occur.

Much more, these interactions may impact on how these drugs work and even its side effects.

Some of these interactions are:

  • Blood thinners
  • Corticosteroids including prednisone
  • Monoamine oxidase inhibitors (MAOIs)
  • There are other antidepressants including Prozac (fluoxetine), Zoloft (sertraline), and Effexor (venlafaxine)
    Antipsychotics such as Risperdal (risperidone) or Haldol (haloperidol)


These are the side effects of Wellbutrin and if you’re experiencing any, it’s best you contact your doctor.

He/she is in the right position to make recommendations and even prescribe the right dosage you should take.

Therefore, this knowledge helps you to know what you will take even if you do.

However, your doctor is in the best position to make these recommendations.



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